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Conversely, adding an SGLT2i to a GLP-1RA did not yield a statistically significant further reduction in HbA1c (SMD 0.11%), suggesting that the glycaemic benefit of combination therapy is predominantly driven by the GLP-1RA component

At the same time, you may have noticed weight gain that feels stubborn, unfamiliar, or out of proportion to your efforts, and weight loss injections such as Ozempic, Mounjaro or Wegovy have entered the conversation

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All-Ericsson et al, 2002)

Nonetheless, further research is needed, including subacute, subchronic, chronic, and genotoxicity studies, to fully evaluate the plant's safety